Book Review: Variability in Human Drug Response

Book Review

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Variability in response to antihypertensive drug treatment.

One of the definitions of the word pragmatic is “practical as opposed to idealistic.” Many of the controversies regarding the issue of the use of race to any degree whatsoever in medical decision-making may be more of a result of tensions between pragmatic and idealistic positions on the issue. The biological determinants of human intraarterial pressure are such that there is no precise cutpoin...

Book Review: System Forensics, Investigation, and Response

Drug metabolism and variability among patients in drug response.

N Engl J Med 2005;352:2211-21. Copyright © 2005 Massachusetts Medical Society. hysicians prescribe drugs on the basis of the characteristics of the medications and on the probability that reliable and reproducible clinical effects will result. However, differences in drug response among patients are common, often leading to challenges in optimizing a dosage regimen for an individual patient. Mo...

Book Review